The DESTINATION Consortium aims to achieve the following throughout duration of the project:

  • Development of an AI discovery platform

  • Validation of an RNano scaffold for therapeutic delivery

  • Creation of an intelligent library of lead cell-internalizing aptamers

  • Animal models for proof-of-concept in vivo CAR-T, mRNA and CRISPR therapies

  • Novel methods based on multicolor single molecule imaging tailored for RNA imaging

  • DNA/RNA origami synthesis and conjugation to RNanos

  • Logic gates (for mRNA protection)

  • Optimised synthesis workflows

  • Communication of outputs via international conferences, workshops and high-impact publications